abstract：:Analysis of cowpox outbreaks revealed an extremely wide range of virus pathogenicity including 9 orders of mammals. Recent serological and virological data support the hypothesis that wild rodents may be a natural reservoir of cowpox virus. Cowpox infection of humans occurring without any contact with infected cattle ...

journal_title：Acta virologica

authors： Marennikova SS,Shelukhina EM,Efremova EV

更新日期：1984-09-01 00:00:00

abstract：:Twenty three strains of simian viruses isolated from nasopharyngeal swabs and respiratory tissues of cynomolgus monkeys showing mild symptoms of respiratory disorders were classified into three groups by their biological, serological and morphological characteristics. Thirteen strains classified as group 1 were judged...

journal_title：Acta virologica

authors： Suzuki M,Nishikawa F,Sasagawa A,Inayoshi T

更新日期：1984-07-01 00:00:00

abstract：:According to the morphology, type and function of its structural components the segmented genome of type C influenza virus is similar to that of influenza viruses A and B. However, type C influenza virus differs from them by the reticular structure of virion surface, absence of the surface glycoprotein neuraminidase, ...

journal_title：Acta virologica

authors： Dobrotvortseva VG,Milovidova NI

更新日期：1984-07-01 00:00:00

abstract：:Histological changes were studied in the central nervous system (CNS) of 58 Macaca rhesus monkeys, infected intracerebrally (i.c.) and subcutaneously (s.c.) with tick-borne encephalitis (TBE) virus. Subacute degenerative process in the CNS occurred in 7 monkeys on days 15-24 post-infection (p.i.), while chronic degene...

journal_title：Acta virologica

authors： Frolova MP,Pogodina VV

更新日期：1984-05-01 00:00:00

abstract：:The structure and cytopathology of obligate intracellular bacteria belonging to families Rickettsiaceae and Chlamydiaceae and their interaction with eukaryotic host cells were compared in electron microscopic studies. "Rickettsia-like" and "chlamydia-like" types of organization of bacterial cells and their interaction...

journal_title：Acta virologica

authors： Avakyan AA,Popov VL

更新日期：1984-03-01 00:00:00

abstract：:A resistant influenza virus has been obtained during successive passages of influenza A virus in 10 to 11-day-old chick embryos (CE) in the presence of 2-(1'-amino-ethyl)-bicyclo(2.2.1) heptane chlorohydrate possessing a high antiviral activity. The virus resistance to the inhibitor was not lost after one passage in t...

journal_title：Acta virologica

authors： Gribkova NV,Kazak NF,Votyakov VI

更新日期：1984-01-01 00:00:00

abstract：:Haemocytes of laboratory bred half-engorged Hyalomma dromedarii ticks phagocytized intracoelomally inoculated Coxiella burnetii organisms. Significantly higher phagocytosis of phase II than phase I C. burnetii was observed, irrespective of whether live, killed untreated or killed organisms treated with chloroform-meth...

journal_title：Acta virologica

authors： Bázliková M,Kazár J,Schramek S

更新日期：1984-01-01 00:00:00

abstract：:Genetic composition and biological properties of influenza virus recombinants A/PR/8/34 (H1N1) and A/Greifswald/6/74 (H3N2) were analysed. The haemagglutinin (HA) gene of the strain A/PR/8/34 was shown an important part of the gene complex determining the virulence for mice, the yield of HA and the plaque forming capa...

journal_title：Acta virologica

authors： Döhner L,Herrmann B,Mentel R,Krenz S

更新日期：1983-11-01 00:00:00

abstract：:Evidence has been obtained indicating the association of certain biological properties of Rickettsia prowazekii with their capacity for persistence. Highly virulent rickettsial cultures inducing increased levels of complement-fixing antibodies were shown to cause a high percentage of rickettsial carriers in infected c...

journal_title：Acta virologica

authors： Ignatovich VF,Barkhatova OI,Rydkina EB

更新日期：1983-11-01 00:00:00

abstract：:Influenza B viruses isolated in 1940, 1950 and 1970 belonged to antigenically remote subgroups according to the antigenic composition of haemagglutinin (HA). Antigenically related strains isolated in 1972-1976 differed by their reproduction capability, by their sensitivity to inhibitors in mammalian sera and by affini...

journal_title：Acta virologica

authors： Korchanova NL,Simanovskaya VK,Sominina AA,Gordon MA,Goloveshkina TN,Kuznetsova EV

更新日期：1983-09-01 00:00:00

abstract：:While the main interest in the pathogenesis of herpes simplex virus (HSV) in the sixties had been focussed on acute infections, in the seventies latent infection has become the main foal of investigation. Despite of overwhelming literature, the HSV persistence has remained a continuing problem from the practical as we...

journal_title：Acta virologica

authors： Rajcáni J,Szántó J

更新日期：1983-09-01 00:00:00

abstract：:Crossing of an attenuated influenza B virus strain (B/Leningrad/14/17/55) passaged at a low temperature with a virulent influenza B virus strain (B/England/2608/76) yielded recombinants similar in the antigenic specificity of their haemagglutinin (HA) and neuraminidase (NA) to B/England/2608/76 strain, but possessing ...

journal_title：Acta virologica

authors： Medvedeva TE,Gordon MA,Ghendon YZ,Klimov AI,Alexandrova GI

更新日期：1983-07-01 00:00:00

abstract：:The discovery of respiratory tract involvement in the pathogenesis of foot-and-mouth disease (FMD) and the recognition of the role of inhalated aerosols in virus transfer opened new outlooks in the epizootology and prophylaxis of the disease. Nevertheless, FMD should be regarded for an infection transmitted by contami...

journal_title：Acta virologica

authors： Röhrer H

更新日期：1983-07-01 00:00:00

abstract：:The cytotoxicity and antiviral activity of the caffeic acid oxidation product (KOP), a higher molecular polyphenolic compound of strong antiviral activity against herpesvirus hominis type 1 and type 2 (HVH 1, HVH 2), were tested in 6 cell cultures: rabbit kidney primary cells (RKP), rabbit testis primary cells (RTP), ...

journal_title：Acta virologica

authors： Thiel KD,Helbig B,Sprössig M,Klöcking R,Wutzler P

更新日期：1983-05-01 00:00:00

abstract：:In the sera of 17 patients with nasopharyngeal carcinoma (NPC) and of 19 patients with tonsillar carcinoma (TC) the titres of IgA, IgG and IgM antibodies to EBV VCA (viral capsid antigen) and of IgG antibodies to EBV EA (early antigen) were determined by the indirect immunofluorescence (IF) method. Significant differe...

journal_title：Acta virologica

authors： Oberender H,Nowak R,Donner A,Kunkel M,Gärtner L,Scholtz HJ

更新日期：1983-05-01 00:00:00

abstract：:Transport properties of 9-(S)-(2,3-dihydroxypropyl) adenine (DHPA) in cell cultures were studied. Transport of DHPA into chick embryo (CE), ZP (a cell line derived from rabbit lungs) and HeLa cells reached equilibrium values after 10 min incubation. The concentration of intracellular DHPA varied from 30 to 50 per cent...

journal_title：Acta virologica

authors： Dragún M,Rada B,Holý A

更新日期：1983-03-01 00:00:00

abstract：:Conditions of the efficient production of tick-borne encephalitis (TBE) virus in chick embryo cell (CEC) monolayer cultures were investigated. The prerequisites of high recovery of the produced virus appeared to be: the use of dense cell monolayers, reasonable frequency of harvests and a suitable buffering of nutrient...

journal_title：Acta virologica

authors： Slávik I,Ciampor F,Mayer V

更新日期：1983-03-01 00:00:00

abstract：:Solid-phase enzyme-immunoassay (EIA) used for the detection of hepatitis A virus (HAV) often reveals a non-specific activity which can be reduced or fully eliminated in the presence of normal serum. The factor responsible for this activity appeared to be a non-viral EIA-active material (NVEAM) that non-specifically re...

journal_title：Acta virologica

authors： Tolskaya EA,Savinskaya SS,Balayan MS,Andzhaparidze AG,Kolesnikova MS

更新日期：1983-01-01 00:00:00

abstract：:The number of E-rosette forming cells and the serum haemagglutination inhibition (HI) antibody titres were examined in 37 volunteers immediately before and 14, 28, 35 and 63 days after immunization with three inactivated influenza virus vaccines A/USSR/92/77 (H1N1)--NIB 6 and in 11 non-vaccinated controls. From the fo...

journal_title：Acta virologica

authors： Schmidt S,Süss J,Oehring H,Schmidt J

更新日期：1982-12-01 00:00:00

abstract：:Structural proteins V1, V2 and V3 of Japanese encephalitis virus (JEV) were isolated and purified by means of polyacrylamide gel electrophoresis (PAGE) in the presence of sodium dodecyl sulfate (SDS) and extracted from the sliced gel. The purified and renatured V3 envelope protein was found to bind to receptors for JE...

journal_title：Acta virologica

authors： Takegami T,Miyamoto H,Nakamura H,Yasui K

更新日期：1982-09-01 00:00:00

abstract：:The cold-adapted temperature-sensitive (ts) influenza virus strain A/Leningrad/134/17/57 (H2N2) multiplied well at 32 degrees C (optimal temperature); lower titres of infectious virus were obtained in developing chick embryos at 40 degrees C. In a canine kidney (MDCK) cell line and in primary calf kidney (CK) cells an...

journal_title：Acta virologica

authors： Garmashova LM,Leontieva GF,Dubrovina TYa,Aleksandrova GI

更新日期：1982-07-01 00:00:00

abstract：:Differences in interfering activities were demonstrated between low-passage epidemic and thermosensitive cold-adapted strains of influenza viruses A and B in experiments on chick embryos inoculated on the chorioallantoic membranes and on white mice. At a high multiplicity of infection the thermosensitive variants show...

journal_title：Acta virologica

authors： Aleksandrova GI,Dekhtyareva NI,Medvedeva TE,Shneider MA

更新日期：1982-05-01 00:00:00

abstract：:The growth properties of pseudorabies virus (PRV) strain V BUK, wild type and its four ts mutants, were examined using highly accurate temperature measurements in the incubator and on the cell sheet. The transition from permissive to nonpermissive temperature occurred within an interval of 1 degree C. The midpoint of ...

journal_title：Acta virologica

authors： Hegenscheid B,Stäber H,Waschke K,Rosenthal HA

更新日期：1982-01-01 00:00:00

abstract：:An abortive infection was induced in L cells by influenza virus A/Hong Kong/68 (H3N2). With the use of antibody and peroxidase-labelled protein A, the localization of virus protein synthesis but not the maturation of virus particles was demonstrated at the ultrastructural level. Five days after inoculation (p.i.), the...

journal_title：Acta virologica

authors： Ciampor F,Sidorenko EV,Taikova NV,Bystrická M

更新日期：1981-11-01 00:00:00

abstract：:A rickettsia-like organism (RLO) was detected in the oocytes of Haemaphysalis inermis ticks. The RLOs were about 5 microns long bent rods with a definite inner structure. They were Gram-negative and could be visualized by Giemsa but not by Gimenez staining. Attempts to cultivate the RLO in chick embryo yolk sacs, vari...

journal_title：Acta virologica

authors： Kovácová E,Rehácek J,Ciampor F

更新日期：1981-09-01 00:00:00

abstract：:The chemical nature of BK virus receptors on human erythrocytes was investigated. Glycosidases, KIO4, proteases, phospholipases and other substances acting specifically on different structures of plasma membranes were used to ascertain the role of surface cell components in the interaction with BK virus. The results o...

journal_title：Acta virologica

authors： Seganti L,Mastromarino P,Superti F,Sinibaldi L,Orsi N

更新日期：1981-07-01 00:00:00

abstract：:The effects of edeine, hygromycin B and alpha-sarcin on the synthesis of virus-specific proteins and formation of infectious virions was studied in cells infected with fowl plague virus (FPV). The manifestation of the antiviral effect of edeine depended on the peculiarities of the FPV strains and the host-cell systems...

journal_title：Acta virologica

authors： Ghendon YuZ,Klimov AI

更新日期：1981-05-01 00:00:00

abstract：:Monoparacoumarylputrescinium chloride (pCPH), supplied to detached leaves of Gomphrena globosa via the petiole, induced interference with tomato bushy stunt virus infection by reducing the number and size of the necrotic local lesions. The phenolic compound neither inactivated directly the virus in vitro, nor induced ...

journal_title：Acta virologica

authors： Pennazio S,Dellamonica G,Redolfi P

更新日期：1981-03-01 00:00:00

abstract：:The lytic activity of splenocytes from C3H mice immunized with a highly attenuated line of Langat virus [tick-borne encephalitis (TBE) complex] was determined by the in vitro 51Cr release assay on TBE virus (western subtype)-infected target L929 cells. After the spleen cell suspensions were depleted of T cells with an...

journal_title：Acta virologica

authors： Gajdosová E,Oravec C,Mayer V

更新日期：1981-01-01 00:00:00

abstract：:Replication of vaccinia virus DNA in chick embryo fibroblasts at a high multiplicity of infection started after 4-6 hr, reached a maximum at the 12th hr and was completed 18 hr after inoculation (p.i.). An analysis of newly synthesised DNAs in the period of the highest rate of synthesis revealed the formation of short...

journal_title：Acta virologica

authors： Chelyapov NV,Chernos VI

更新日期：1981-01-01 00:00:00

abstract：:Chronic infection of HeLa cells was induced by an attenuated variant of Japanese encephalitis (JE) virus (HeLa-K3 cell line). The chronic infection was characterized by alternating phases of degeneration and recovery of the cell monolayer. JE virus was regularly released into the medium of chronically infected cell cu...

journal_title：Acta virologica

authors： Loginova NV,Deryabin PG,Mikhailova GR,Tsareva AA,Buinitskaya OB

更新日期：1980-12-01 00:00:00

abstract：:Nonlethal infection was induced in laboratory mice with sublethal doses of rabies strains isolated from small wild rodents. Three types of nonlethal infecion were observed: persistent--with virus irregularly reisolable for at least 56 days after inoculation: latent--with negative virus reisolation but presence of infe...

journal_title：Acta virologica

authors： Sodja I

更新日期：1980-09-01 00:00:00

abstract：:Splenocytes from mice immunized intravenously with one dose of Langat or Yellow fever viruses were cytotoxic for target cells infected with virulent tick-borne encephalitis (TBE) virus; cytotoxicity was measured by 51Cr release from target L929 cells. No significant lysis of the TBE virus-infected taget cells with spl...

journal_title：Acta virologica

authors： Gajdosová E,Mayer V,Oravec C

更新日期：1980-06-01 00:00:00

abstract：:Cell-mediated reactions in measles cases, in direct contacts and healthy children were tested. Indices of phytohaemagglutinin-stimulated blastic transformation and leukocyte migration inhibition were evaluated. Positive reactions were found in the first and second weeks after manifestation of clinical symptoms. The ap...

journal_title：Acta virologica

authors： Kańtoch M,Abramow-Newerly W,Jankowski M,Imbs D,Litwińska B,Stepień R,Slowińska I,Kubica J,Boguslawska J

更新日期：1980-03-01 00:00:00

abstract：:Homology between DNAs of some orthopoxviruses: vaccinia, neurovaccinia, cowpox, ectromelia, variola and white-pox was studied. By the method of molecular hybridization of labelled virion DNAs of the viruses studied with an excess of unlabelled vaccinia DNA and further treatment of the hybridized products by the single...

journal_title：Acta virologica

authors： Chernos VI,Surgai VV

更新日期：1980-03-01 00:00:00

abstract：:In 1977, 477 small birds of 52 species were virologically examined. Five cloacal swabs from Troglodytes troglodytes yielded two paramyxovirus strains which were found antigenically related to, but not identical with Ch/Yucaipa/California/56 virus according to three serological tests. The ecological significance of the...

journal_title：Acta virologica

authors： Tůmová B,Stumpa A,Janout V,Uvízl M,Chmela J

更新日期：1979-11-01 00:00:00

abstract：:The binding of immune and preimmune rabbit sera to fixed VERO cells infected with herpes simplex virus type 1 (HSV 1) was measured by quantitative immunofluorescence. False positive binding of the preimmune serum (PS) occurred from 8 hr post infection (p.i.), while the immune serum (IS) revealed positive fluorescence ...

journal_title：Acta virologica

authors： Rajcáni J,Hulíková Z,Mucha V

更新日期：1979-09-01 00:00:00

abstract：:For the quantitative assay of selected togaviruses, suspensions of BHK cells were inoculated with virus and grown in spinner cultures. At intervals, dependent on the growth characteristics of the viruses, about 10(3) cells were centrifuged on to microscope slides and then stained with fluorescent antibody. For rapid d...

journal_title：Acta virologica

authors： Enzmann PJ

更新日期：1979-07-01 00:00:00

abstract：:The uses of the nonionic detergent Triton X-100 (TX-100) and the cationic cetyltrimethylammonium bromide (CTAB) for the production of tick-borne encephalitis (TBE) virus subunits were compared. TX-100 splitted the virus into haemagglutinating envelope components which contain the virion proteins V3 and V1 and into a l...

journal_title：Acta virologica

authors： Heinz F,Kunz C

更新日期：1979-05-01 00:00:00

abstract：:Viraemia was studied in adult Clethrionomys glareolus subcutaneously infected with 12 strains of tick-borne encephalitis (TBE) virus isolated in western and eastern foci of TBE. Nine strains caused viraemia regularly or irregularly, reaching titres higher than the threshold level of TBE virus infectivity for its vecto...

journal_title：Acta virologica

authors： Chunikhin SP,Kurenkov VB

更新日期：1979-05-01 00:00:00